Phytocannabinoids

Phytocannabinoid,Phytocannabinoids are cannabinoids that occur naturally in the cannabis plant. The classical cannabinoids are formed through decarboxylation of their respective 2-carboxylic acids (2-COOH), a process which is catalyzed by heat, light or alkaline conditions. These cannabinoids are abundant in the viscous resin that is produced by glandular structures in the cannabis plant called trichomes. This […]

Endocannabinoid receptors

Endocannabinoid receptors, The endocannabinoid system consists of the endogenous cannabinoids (endocannabinoids), cannabinoid receptors and the enzymes that synthesise and degrade endocannabinoids. Many of the effects of cannabinoids and endocannabinoids are mediated by two G protein-coupled receptors (GPCRs), CB(1) and CB(2), although additional receptors may be involved. CB(1) receptors are present in very high levels in […]

Cannabidiol sciense

Cannabidiol sciense, Many physicians refrain from approving Cannabis use by patients because they learned nothing about Cannabis in medical school and cannot knowledgeably advise patients about dosage, side effects, mechanism of action, etc. This talk, published by the Americans for Safer Access (ASA) and including the particpation of UCSF oncologist/AIDS specialist Donald Abrams, M.D. to […]

CBD EndoCannabidiol system

CBD EndoCannabidiol system, Cannabis has been at the center of one of the most exciting—and underreported—developments in modern science. Research on marijuana’s effects led directly to the discovery of a hitherto unknown biochemical communication system in the human body, the Endocannabinoid System, which plays a crucial role in regulating our physiology, mood, and everyday experience. The […]

CBD PTSD

CBD PTSD, Endocannabinoid (eCB) signaling has been identified as a modulator of adaptation to stress, and is integral to basal and stress-induced glucocorticoid regulation. Furthermore, interactions between eCBs and glucocorticoids have been shown to be necessary for the regulation of emotional memories, suggesting that eCB function may relate to the development of post-traumatic stress disorder […]

CBD Alzheimer disease

CBD Alzheimer disease, Alzheimer’s disease (AD) is frequently associated with neuropsychiatric symptoms (NPS) such as agitation and aggression, especially in the moderate to severe stages of the illness. The limited efficacy and high-risk profiles of current pharmacotherapies for the management of agitation and aggression in AD have driven the search for safer pharmacological alternatives. Over […]

CBD Migraine headache

CBD Migraine headache, When talking about the therapeutic effects of CBD, it’s often the cannabinoid’s pain reducing ability that is mentioned. As headaches are the most common source of pain in the general population, it would make sense then that CBD could be an interesting therapeutic target. While the cannabis plant is mentioned as a […]